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Centers & Research Cores

About the MPRINT Hub Centers

There are three parts and six cores to the MPRINT Hub. The first part is the Indiana University-Ohio State University Data and Model Knowledge and Research Coordination Center (IU-OSU DMKRCC).

Diagram of the teams showing IU-OSU MPRINT-DMKRCC lead by MPI’s Quinney and Li in the middle of a circle. Five teams ring the circle: Logistics Core (Quinney and Li; Knowledgeable and Portal Core (Li); Real World Evidence Core (Mendonca/Bartlett); Outreach Core (Quinney); Pharmacometrics and Clinical Trial Design Core (Mies and Quinney).

The DMKRCC serves as the administrative core of the MPRINT Hub and provides expertise in pharmacometrics and clinical trial design. It also supports real-world data analysis, and will collate data related to maternal and pediatric pharmacology into an openly accessible knowledgebase.

Learn more about the IU-OSU DMKRCC

Then there are two Centers of Excellence in Therapeutics (CETs). The Vanderbilt University CET and the University of California San Diego CET support innovative translational research programs aimed to enhance precision pharmacology in maternal and pediatric populations.

Discover what the six MPRINT Cores are working on

Knowledgebase & Portal Core

The Knowledgebase & Portal core is developing a knowledgebase of data and resources relating to maternal and pediatric therapeutics.

Pharmacometrics & Clinical Trial Design Core

The Pharmacometrics & Clinical Trial Design Core is applying machine learning and various models to provide new expertise during clinical and adaptive trials.

Real-world Evidence Core

The Real-world Evidence Core brings together researchers from across the U.S. to build up and support robust real-world data resources.

Phenotyping Core

The Phenotyping Core at Vanderbilt University provides unique expertise in electronic health records and innovative new ways of understanding responses to medications.

Milk Analytics Core

The Milk Analytics Core collects human milk samples and processes those samples for various assays.

Pharmacometric and Analytical Chemistry Core

Housed at UC San Diego, the Pharmacometric and Analytical Chemistry Core performs tests on various samples like plasma, tissue, and breast milk.